Research on the causes and the potential therapeutics for the Coronavirus (originally published April 30th, 2020, only the title & subtitle has changed since publication.)

A news & analysis of the research and therapeutics around the Covid-19 disease and the Sars-CoV-2 virus’s impact on human biology written up by Micah Blumberg, Neurohacker, Journalist, and WebXR A-Frame Software Architect at Silicon Valley Global News http://svgn.io http://vrma.io

Chapter 1: The main attack vectors

First thing to know is that when someone is infected with Sars-Cov-2 there are two main receptor paths for it to attack your cells ACE2 and CD147.

LIGANDAL | REGENERATIVE PEPTIDES
Our peptide scaffolds will bolster the immune response to SARS-CoV-2. These scaffolds will also bind to the ACE2…www.ligandal.com

Blood cells and the endothelium have the ACE2 receptor, and T-cells (your immune cells) have the CD147-spike protein.

ACE2

“Angiotensin-converting enzyme 2 (ACE2)[5] is an enzyme attached to the outer surface (cell membranes) of cells in the lungs, arteries, heart, kidney, and intestines.[6][7] ACE2 lowers blood pressure by catalysing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1–7) (a vasodilator).[8][9][10] ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1–7)[11] making it a promising drug target for treating cardiovascular diseases.[12][13]

ACE2 also serves as the entry point into cells for some coronaviruses.[5] The human version of the enzyme is often referred to as hACE2.[14]”

Angiotensin-converting enzyme 2
ACE2 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes Identifiers Aliases ACE2, ACEH…en.wikipedia.org

Note: Angiotensin-converting enzyme 2 is located on the surface of endothelial and other cells.[15]

Note2: Endothelium is a single layer of squamous endothelial cells that line the interior surface of blood vessels, and lymphatic vessels.

Endothelium
Endothelium is a single layer of squamous endothelial cells that line the interior surface of blood vessels, and…en.wikipedia.org

CD147

“SARS-CoV-2 invades host cells via a novel route: CD147-spike protein“

SARS-CoV-2 invades host cells via a novel route: CD147-spike protein
Currently, COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been widely spread…www.biorxiv.org

“SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion”

“(…)In other words, these results tell us that T lymphocytes may be more permissive to SARS-CoV-2 infection and less permissive for SARS-CoV infection, similar to the findings in a previous study. Therefore, it is plausible that the S protein of SARS-CoV-2 might mediate potent infectivity, even on cells expressing low hACE2, which would, in turn, explain why the transmission rate of SARS-CoV-2 is so high. It is also possible that other receptors mediate the entry of SARSCoV-2 into T cells, such as CD147, present on the surface of T lymphocytes, which was recently reported to be a novel invasive route for SARS-CoV-2.9”

“Novel coronavirus attacks and destroys T cells, just like HIV”

“the team found that unlike HIV that replicates faulty T cells, the coronavirus does not replicate, showing that the T cells and the virus may end up dying together.” It’s thought that T cells will not replicate the virus, but since other cells do replicate the virus the fear is that the immune system might become compromised.

Novel coronavirus attacks and destroys T cells, just like HIV
The immune system has many components that work together in protecting the body from foreign invaders. One of the most…www.news-medical.net

“Coronavirus could attack immune system like HIV by targeting protective cells, warn scientists”

Covid-19 may attack immune system like HIV, doctors fear
Researchers in China and the US find that the virus that causes Covid-19 can destroy the T cells that are supposed to…www.scmp.com

“Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)” “T cells were dramatically reduced in COVID-19 patients, especially among elderly patients (≥60 years of age) and in patients requiring Intensive Care Unit (ICU) care. Counts of total T cells, CD8+T cells or CD4+T cells lower than 800/μL, 300/μL, or 400/μL, respectively, are negatively correlated with patient survival.”

Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)
BACKGROUND The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus…www.medrxiv.org

Perhaps if there are enough T cells, killer t cells, bcells and antibodies will be enough to trap and end the viral contagion inside the body

“SARS-CoV-2: How a person’s immune system defeated the virus”

SARS-CoV-2: How a person's immune system defeated the virus
Although some people who contract SARS-CoV-2 experience serious symptoms, others are able to recover after a fairly…www.medicalnewstoday.com

Chapter 2: The Main Symptoms

March 24, 2020 “COVID-19 symptoms can be all or nothing: ‘This virus just has the whole kit and caboodle’”

COVID-19 symptoms can be all or nothing: 'This virus just has the whole kit and caboodle'
CLOSE For Elizabeth Schneider, her bout withthe coronavirus began with a scratchy throat, exhaustion and a headache…www.news-press.com

“(…) data collected by state officials show the most common underlying health conditions among Oregonians who have died from COVID-19.

“Heart disease is the most frequent ailment. Neurological or neurodevelopmental conditions are second most common.

“Diabetes, lung disease and illnesses such as cancer are also on the list.”

Coronavirus in Oregon (April 30): Heart disease most common illness linked to fatal cases
New data collected by state officials show the most common underlying health conditions among Oregonians who have died…www.oregonlive.com

“The SARS-CoV-2 outbreak: What we know”

“Symptom of CoVID-19 are non-specific and the disease presentation can range from no symptoms (asymptomatic) to severe pneumonia and death.”

“the most common symptoms were fever (98%), cough (76%), myalgia or fatigue (44%); and atypical symptoms included sputum (28%), headache (8%), hemoptysis (5%) and diarrhea (3%).”
“Complications included acute respiratory distress syndrome (29%), acute heart injury (12%), and secondary infections (10%);”
”NanShan Zhong’s team (Weijie et al., 2020) found that the most common symptoms were fever (87.9%), cough (67.7%), diarrhea (3.7%) and vomiting (5.0%). 25.2% of the patients had at least one underlying disease (such as hypertension, chronic obstructive pulmonary disease).”

The SARS-CoV-2 outbreak: What we know
The latest summary of the COVID-19 outbreak in China; * There might be an oral-fecal transmission of the virus; *…www.sciencedirect.com

This video (below) was seen by 16 million people. What if he was exhausted because of the virus? Exhaustion is a symptom.

“Overworked Chinese doctor collapses from exhaustion”

Here we had a video of a Dutch minister passing out in Parliament

When I saw videos and rumors of people falling from exhaustion for me that caused me to begin taking a supplement called D-Ribose, this was either late January or early February. I will talk more about this in the 5th section.

Co-Morbidities

“Preventing a covid-19 pandemic BMJ 2020; 368 doi: https://doi.org/10.1136/bmj.m810 (Published 28 February 2020)”

“The largest Chinese study with 44,672 confirmed cases of Covid-19 shows a high overall case fatality rate (CFR) of 2.3% [2]. Important co-morbidities are hypertension (CFR 6.0%), diabetes (CFR 7.3%), cardiovascular disease (CFR 10.5%) and age >70 (CFR 10.2%) [2]. Similar co-morbidities were noted for the SARS outbreak in 2003. “It is widely unclear what the commonality of these risk factors is. This is somehow surprising as compared to for example the 2009 pandemic H1N1 influenza outbreak, immunosuppressant patients were primary affected. Cardiac patients seem to be at higher risk in Covid-19. One possible answer could be the following: Patients with the comorbidities of hypertension, diabetes and cardiovascular disease might fulfil the indication for the use of angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists [3].”

Re: Preventing a covid-19 pandemic: ACE inhibitors as a potential risk factor for fatal Covid-19
Dear Editor, The coronavirus disease 2019 (Covid-19) outbreak from Wuhan, China, is spreading worldwide and is a major…www.bmj.com

I remember that Andre Watson the CEO of Ligandal posted his excellent research on the Neurological effects of the Coronavirus early on. I remember people in a “virus study group” were mocking the idea that a respiratory virus was also causing neurological effects, but Andre was right. You can check out Andre’s work at www.ligandal.com

However the idea that the covid-18 disease has neurological symptoms isn’t a controversy, it’s actually mainstream news

04/13/2020 “Coronavirus May Also Cause Neurological Symptoms, Like Headaches”

Coronavirus May Also Cause Neurological Symptoms, Like Headaches
Fever, cough, shortness of breath are the key signs that come to mind with the novel coronavirus, but a new report from…www.huffpost.com

Mainstream News confirmation of neurological effects of the coronavirus.

27 APRIL 2020 “Coronavirus Patients Are Reporting Neurological Symptoms. Here’s What You Need to Know”
“COVID-19 can also infect cells outside of the respiratory tract and cause a wide range of symptoms from gastrointestinal disease (diarrhoea and nausea) to heart damage and blood clotting disorders. It appears that we have to add neurological symptoms to this list, too.”

Coronavirus Patients Are Reporting Neurological Symptoms. Here's What You Need to Know
As case numbers of COVID-19 continue to rise around the world, we are starting to see an increasing number of reports…www.sciencealert.com

APRIL 6, 2020 “Mysterious Heart Damage, Not Just Lung Troubles, Befalling COVID-19 Patients”

Mysterious Heart Damage, Not Just Lung Troubles, Befalling COVID-19 Patients
Most of the attention in the COVID-19 pandemic has been on how the virus affects the lungs. But evidence shows that up…khn.org

Chapter 3: Research on potential therapeutics

Mar 17, 2020 Video “Coronavirus and the Heart: Do ACE Inhibitors and ARBs Increase Covid-19 Mortality?”

The video says that Ace inhibitors are very commonly used in the conditions associated with increased mortality in coronavirus, Cardiovascular disease, Diabetes, Chronic respiratory disease, hypertension, and cancer. In another part of the video Ace inhibitors are hypothesized as being harmful, in another part of the video they are cited as potentially beneficial to patients. The video does not offer a conclusion as to which notion (are ACE inhibitors helpful or harmful) is correct as research is ongoing.

The video linked above included a link to this citation: “Angiotensin receptor blockers as tentative Sars-CoV-2 therapeutics.” This paper says “Notably, angiotensin‐converting enzyme (ACE) and its close homologue ACE2, while both belonging to the ACE family of dipeptidyl carboxydipeptidases, serve two opposing physiological functions. ACE cleaves angiotensin I to generate angiotensin II, the peptide which binds to and activates AT1R to constrict blood vessels, thereby elevating blood pressure. By contrast, ACE2 inactivates angiotensin II while generating angiotensin 1–7, a heptapeptide having a potent vasodilator function via activation of its Mas receptor (Santos et al., 2003), and thus serving as a negative regulator of the renin–angiotensin system. These opposing actions of ACE and ACE2 were recently reviewed by Smyth, Cañadas‐Garre, Cappa, Maxwell, & McKnight, 2019.”

Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics
At the time of writing this commentary (February 2020), the coronavirus COVID‐19 epidemic has already resulted in more…onlinelibrary.wiley.com

What is cited above establishes that ACE and ACE2 are essentially opposites. For example ACE may constrict blood vessels, while ACE2 may vasodilate.

“ACE2 of the heart: From angiotensin I to angiotensin (1–7).”
“The ACE homologue ACE2 efficiently hydrolyses Ang II to form Ang (1–7), a peptide that exerts actions opposite to those of Ang II. “

ACE2 of the heart: From angiotensin I to angiotensin (1-7).
Cardiovasc Res. 2007 Feb 1;73(3):463-9. Epub 2006 Sep 19. Reviewwww.ncbi.nlm.nih.gov

It’s interesting how the ACE2 receptor acts on Angiotensinogen ANG II to vasodilate your lymph nodes and your blood vessels and how the Angiotensinogen regulates T cells.

Regulation of T-cell function by endogenously produced angiotensin II.
Am J Physiol Regul Integr Comp Physiol. 2009 Feb;296(2):R208-16. doi: 10.1152/ajpregu.90521.2008. Epub 2008 Dec 10…www.ncbi.nlm.nih.gov

Regulation of T-cell function by endogenously produced angiotensin II

“These findings contribute to our understanding of how ANG II and T cells enhance inflammation in cardiovascular disease.”

Regulation of T-cell function by endogenously produced angiotensin II
the renin-angiotensin system (RAS) is a prominent mediator of hypertension and a key target in the treatment of this…journals.physiology.org

Here we have a paper from 2009 called “Chronic Use of Angiotensin Pathway Inhibitors Is Associated with a Decreased Risk of Acute Respiratory Distress Syndrome.”

Title
This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Find out more.www.atsjournals.org

This paper suggests that ACE inhibitors decrease the risk of ARDS, which is a condition that is associated with the Coronavirus.

“Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II-induced inflammation.”

Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms…
J Am Soc Nephrol. 2007 Apr;18(4):1093-102. Epub 2007 Feb 28. Research Support, N.I.H., Extramural; Research Support…www.ncbi.nlm.nih.gov

So what I am learning from the above links is that ACE2 receptors effect the renin-angiotension system which effects whether or not T cells and NK natural killer cells amplify inflammation.

“Regulation of T-cell function by endogenously produced angiotensin II”
“the renin-angiotensin system (RAS) is a prominent mediator of hypertension and a key target in the treatment of this disease. ANG II has myriad effects on the cardiovascular system. In many tissues, ANG II activates the NADPH oxidase to produce reactive oxygen species (ROS) (16). In the cardiovascular system, this effect of ANG II has been linked to the induction of cardiac hypertrophy, inflammation, lipid oxidation, endothelial dysfunction, and ultimately increased blood pressure (4).”

Regulation of T-cell function by endogenously produced angiotensin II
the renin-angiotensin system (RAS) is a prominent mediator of hypertension and a key target in the treatment of this…journals.physiology.org

“Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury”

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury
Since March 2013, the emergence of an avian-origin influenza A (H7N9) virus has raised concern in China. Although most…www.nature.com

“Moreover, ACE2 deficiency worsened the disease pathogenesis markedly, mainly by targeting the angiotensin II type 1 receptor (AT1). The current findings demonstrate that ACE2 plays a critical role in influenza A (H7N9) virus-induced acute lung injury and suggest that might be a useful potential therapeutic target for future influenza A (H7N9) outbreaks.”

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury
Since March 2013, the emergence of an avian-origin influenza A (H7N9) virus has raised concern in China. Although most…www.nature.com

So when your ACE2 goes missing, the progression of the H7N9 disease worsened, because some how the ACE2 was preventing or reducing your lung injury from H7N9. So what happens when you have a virus that eats ACE2 receptors specifically?

“In this paper, we report that angiotensin-converting enzyme-2 (ACE2) protected against severe lung injury induced by RSV infection”

Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus
Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory illness in infants and young…www.nature.com

Chapter 4: The mystery of the Blood Clots

April 24, 2020 “Blood Clots Are Another Dangerous COVID-19 Mystery”

““Patients are making clots all over the place,” says Adam Cuker, MD, a hematologist and associate professor of medicine at the Hospital of the University of Pennsylvania. “That’s making management of these patients very challenging.””

Blood Clots Are Another Dangerous COVID-19 Mystery
April 24, 2020 -- Hooman Poor, MD, was tired of watching his patients die, and it looked like another was slipping…www.webmd.com

APRIL 27, 2020 “Tiny blood clots may make coronavirus more deadly, doctors say”
“Poor and Marrazzo speculated that the virus somehow damages human cells in a way that promotes clotting. Poor noted that COVID-19 patients have elevated levels of D-dimer, a small protein fragment produced by blood clots.”

Tiny blood clots may make coronavirus more deadly, doctors say
The COVID-19 coronavirus appears to promote blood clotting throughout the body, which might help explain why it is so…www.cbsnews.com

“Coronavirus Pandemic Update 61: Blood Clots & Strokes in COVID-19; ACE-2 Receptor; Oxidative Stress”

This video explains how the Coronavirus is causing blood clots and what’s mind blowing is that it explains to me how the D-ribose I have been taking could be a potential treatment for the Coronavirus! In this video posted above I learned how Sars-Cov2 in degrading the ACE2 receptors is (Ace2 receptors vasodilate and reduce inflammation) leading events like vasoconstriction which may lead to increased blood pressure, pulmonary edema and ARDS, increased the blood clot problems like those we are now seeing in the news causing strokes and heart attacks in young people in their 30s. The virus binds ACE2 and degrades it taking it out of circulation so you get all the symptoms we are seeing the coronavirus cause, the virus takes ACE2 out of the endothelium specifically eventually causing the vasoconstriction, the blood clots, the neurological disease, organ failure, heart attack, stroke, and the oxidative stress and inflammation.

My thought on co-morbidities with coronavirus is that perhaps a combination of the T-cells being attacked, the immune system being compromised, the immune cells causing inflammation because the renin–angiotensin system is out of wack, perhaps in part because the ACE2 have been consumed by Sars-CoV-2, all of this is like taking the brakes off the cars that represent all the other disease a person has (which at the root may also stem from or be worsened by inflammation and oxidation).

Chapter 5: Treating Oxidative Stress

“The role of ribose on oxidative stress during hypoxic exercise: a pilot study.”

“Oxygen free radicals are produced during stress, are unstable, and potentially interact with other cellular components or molecules. This reactivity can influence cellular function, including a prolongation in tissue recovery following exercise. We tested the effect of ribose (d-ribose), a pentose carbohydrate, in a double-blinded, crossover study on markers of free radical production during hypoxic exercise.“

The role of ribose on oxidative stress during hypoxic exercise: a pilot study.
J Med Food. 2009 Jun;12(3):690-3. doi: 10.1089/jmf.2008.0065. Clinical Trialwww.ncbi.nlm.nih.gov

“Cellular protection during oxidative stress: a potential role for D-ribose and antioxidants.”

“Exogenous reducing antioxidant agents, such as vitamin C and/or E, play a role in addressing these formed species; however, recent research has suggested that fruit seed extracts may provide additional cellular benefits beyond their antioxidant features. Furthermore, supplemental D-ribose enhances the recovery of high-energy phosphates following stress and appears to potentially offer additional benefits by reducing radical formation. Specifically, during periods of hypoxia/ischemia, supplemental D-ribose may play an inhibitory role in the breakdown of adenine nucleotides, influencing the subsequent formation of xanthine and uric acid compounds; and thereby affecting the release of superoxide anion radicals. The combination of D-ribose with reducing antioxidants may provide a more optimal state of cellular protection during and following times of oxidative stress.”

Cellular protection during oxidative stress: a potential role for D-ribose and antioxidants.
A healthy cellular system involves the maintenance of an intracellular metabolic balance. Reactive oxygen species (ROS)…www.ncbi.nlm.nih.gov

“Cell Death and Autophagy under Oxidative Stress: Roles of Poly(ADP-Ribose) Polymerases and Ca2+”

“Oxidative stress induces DNA damage, activating PARP1 and PARP2. Activated PARP signals downstream into DNA repair processes and cell death pathways. It is therefore a key factor in the maintenance of genomic stability“

Cell Death and Autophagy under Oxidative Stress: Roles of Poly(ADP-Ribose) Polymerases and Ca2+
On the cellular level, oxidative stress may cause various responses, including autophagy and cell death. All of these…www.ncbi.nlm.nih.gov

What happens if you put ACE2 back into the body?

“Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

https://www.cell.com/cell/fulltext/S0092-8674(20)30399-8?rss=yes&fbclid=IwAR0j8wdLz_DY5O9pV_v6-F2g-AhGHlSguvofTjK6xVyxuoAJQBPsCabtf0I

“DPP-4 Inhibitors as Potential Candidates for Antihypertensive Therapy: Improving Vascular Inflammation and Assisting the Action of Traditional Antihypertensive Drugs”

“As a differentiation antigen on the surface of T cells, DPP-4/CD26 plays an important role in regulating the activation and chemotaxis of mononuclear-macrophages, NK cells, and T cells. DPP-4 inhibitors can regulate anti-inflammatory and anti-hypertensive effects by regulating the functions of these immune cells, especially T cells. We found that DPP-4i exhibits strong inhibitory effects on inflammation and oxidative stress,”

DPP-4 Inhibitors as Potential Candidates for Antihypertensive Therapy: Improving Vascular…
Dipeptidyl peptidase-4 (DPP-4) is an important protease that is widely expressed on the surface of human cells and…www.frontiersin.org

“5 Natural ACE Inhibitors: Health Effects & Limitations”

“Please note: remember to speak with your physician before taking any supplements and let them know about all the supplements and over-the-counter drugs you are currently taking. They’re not meant to replace your medical treatment and may interact with certain drugs.”

5 Natural ACE Inhibitors: Health Effects & Limitations - SelfHacked
In recent years, scientists have found numerous natural compounds that potentially work like ACE inhibitors, a class of…selfhacked.com

“High Blood Pressure and ACE Inhibitors”

“Angiotensin converting enzyme (ACE) inhibitors are high blood pressure drugs that widen or dilate the blood vessels to improve the amount of blood the heart pumps and to lower blood pressure. ACE inhibitors also increase blood flow, which helps to decrease the amount of work your heart has to do and can help protect your kidneys from the effects of hypertension and diabetes.”

High Blood Pressure and ACE Inhibitors
Angiotensin converting enzyme (ACE) inhibitors are high blood pressure drugs that widen or dilate the blood vessels to…www.webmd.com

ACE Inhibitors (your number one ACE inhibitor is your ACE2, but if coronavirus ate your ACE2 then what are you going to do? Talk to your doctor first, don’t take the wrong one!)

“Patients who develop a cough from an ACE inhibitor need to ask their physician about angiotensin receptor blockers (ARBs). ACE inhibitors slow down the production of angiotensin II, while ARBs (as the name says) block the influence of angiotensin II by locking up cells’ receptors for it.”

ACE Inhibitors | Dr. Sinatra's HeartMD Institute
By Stephen T. Sinatra, M.D., F.A.C.C., F.A.C.N., C.N.S., C.B.T. Drugs in this class are lisinopril (Prinivil)…heartmdinstitute.com

As late as April 26 we had an article that said

“We Still Don’t Know How the Coronavirus Is Killing Us”

We Still Don't Know How the Coronavirus Is Killing Us
We're committed to keeping our readers informed. We've removed our paywall from essential coronavirus news stories…nymag.com

I think that at the root level it’s inflammation and oxidative stress that leads to organ failure, being unable to breath, having low blood oxygen levels etc. Remember to take all your vitamins, essential oils, omega3, vitamin C, vitamin D, D-ribose.

and Zinc

“Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture”

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores…
Author Summary Positive-stranded RNA (+RNA) viruses include many important pathogens. They have evolved a variety of…journals.plos.org

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores…
Increasing the intracellular Zn 2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the…www.ncbi.nlm.nih.gov

“D-Ribose for Fibromyalgia and Chronic Fatigue Syndrome”

“One small study published in The Journal of Alternative and Complementary Medicine concluded that d-ribose supplementation significantly improved symptoms of these conditions, including:”

A Type of Sugar to Treat Fibromyalgia & Chronic Fatigue Syndrome?
D-ribose is a supplement that's sometimes recommended as a treatment for people with fibromyalgia and chronic fatigue…www.verywellhealth.com

“The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study.”

“CONCLUSIONS: D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome.”

The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study.
OBJECTIVES: Fibromyalgia (FMS) and chronic fatigue syndrome (CFS) are debilitating syndromes that are often associated…www.ncbi.nlm.nih.gov

“How Ribose Improves Your Daily Energy”

“A key molecule, called adenosine triphosphate (or ATP for short), is known as the energy currency of the cell because the amount of ATP we have in our tissues determines whether we will be fatigued, or will have the energy we need to live vital, active lives. Ribose provides the key building block of ATP, and the presence of ribose in the cell stimulates the metabolic pathway our bodies use to actually make this vital compound. If the cell does not have enough ribose, it cannot make ATP. So, when cells and tissues become energy starved, the availability of ribose is critical to energy recovery.”

EndFatigue
Ribose is a simple, five-carbon sugar that is found naturally in our bodies. But ribose is not like any other sugar…secure.endfatigue.com

“An experimental peptide could block COVID-19”

An experimental peptide could block COVID-19
In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that…medicalxpress.com

My belief is that D-Ribose, Vitamins C & D, Antioxidants, and Zinc could provide immediate relief for Coronavirus patients and that actually effective medicine should be on the way soon with the new emerging understanding of Sars-Cov-2.

End of Article.

About the author of this page: Micah Blumberg

I’m a neurohacker. I study this topic, neural lace, I have a group focused on it with 2,400 members. Its called Self Aware Networks: Computation Biology: Neural Lace and the idea is that your computational biology is rendering a volumetric video stream, a simulation, when your awake, and that we can tap into that with medical imaging technologies for two way data transmission, downloading what your eyes see, what your ears hear, and bringing AR VR like experiences without glasses via direct brain stimulation. I also have a podcast called the Neural Lace Podcast and I hosted Neurotech SF meetups for two years where I led a team that brought eeg into Webxr. My latest project is a webxr magazine for a news channel I started called Silicon Valley Global News intended to be on the front lines of science and technology. I’ve been self studying biology and computer science related topics for 14 years or so I estimate. Example of my software https://twitter.com/worksalt/status/1214759820521177090?s=20